The article focuses on the influence of gender on structural discourse markers in the English popular-science genre of TED talks. The research is based on 20 English lectures (10 male and 10 female ones). All the lectures highlight the problems of education and online learning. The overall study materials comprise about 50,000 words. The structural discourse markers include global and local ones. Local structural discourse markers are used to connect statements, express the relations of cause, effect, time, condition, exclusion, inclusion.